An ALS hot spot in the French Alps associated with genotoxic fungi

by melenaboijaon 3/11/2025, 12:20 AMwith 1 comments

by robocaton 3/11/2025, 4:24 AM

Summary:

  P.S. asked whether wild fungi (specifically, False Morels) that generate a genotoxin (monomethylhydrazine) related by mechanism to cycad methylazoxymethanol, a leading candidate for the etiology of Guam ALS, might have been used as a food item in Montchavin. This question generated a more intensive examination of the sources and uses of food items (notably wild mushroom species) by the Montchavin-related ALS cases and controls, whereupon the link between ALS and False Morels was discovered.