I've got a Cloudflare support ticket that's been open since 8th August relating to R2, and it seems others may have a similar issue:
https://community.cloudflare.com/t/r2-intermittent-500-errors-on-put/485134
This is one of two CF services we use, and I'm wondering how people feel about CF and its support these days?
You might have more luck asking on discord: https://discord.com/invite/cloudflaredev
With the way Cloudflare works I'd say R2 is still a relatively young product and hasn't been heavily battle tested.
There are a lot of stable and working products.
And to support, well don't depend on it! If it works it works.
You can email me (jgc@cloudflare) with the ticket number and I'll take a look.